As another new year gets under way, many of us will be looking for a way of boosting how we feel, but is it better to hit the gym or meditate in nature? Now new research by Swansea experts has provided the largest ever comparison of well-being-focused interventions delivered to adults.
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The team reviewed 183 randomized controlled trials, representing almost 23,000 participants, and evaluated 12 categories of interventions ranging from psychological, physical, mind–body, and nature-based approaches to find out more. Their research was the first interdisciplinary comparison carried out across psychological, physical, mind-body and environmental interventions.
The study, which has been published Nature Human Behaviour, gives an integrated view of how different disciplines contribute to well-being. By focusing on general adult samples rather than clinical groups, it provides evidence that will be relevant to developing public health, education, workplace well-being, and community programs.
The researchers' key findings were:
First author Dr. Lowri Wilkie, from the School of Psychology, said, "Our analysis shows that there is no single route to improving well-being. Mindfulness, compassion-based approaches, yoga, exercise and positive psychology interventions all showed moderate benefits compared with control groups, and combining physical activity with psychological interventions appeared particularly promising.
"By using network meta-analysis, we were able to compare very different interventions from different disciplines within one framework, giving policymakers and practitioners a much clearer view of the range of effective options available for building well-being in the general population."
Because interventions were tested in general populations, the evidence is directly relevant to population well-being strategies, including efforts to enhance resilience and support mental health before problems escalate. The study's results complement the Swansea-led GENIAL framework, which emphasizes well-being as being grounded by connection to self, to others, and to nature.
Senior author Professor Andrew Kemp added, "What this study makes clear is that well-being can be supported through multiple, evidence-based pathways. Psychological interventions, exercise and mind–body practices all perform well, which means services and policymakers have real flexibility to design programs that fit different settings and preferences.
"For us, this paper also marks an important milestone in a long-running collaboration between Swansea University and Swansea Bay University Health Board, and it highlights how rigorous, interdisciplinary research can inform population-level approaches to mental health and well-being."
Co-author Dr. Zoe Fisher, a consultant clinical psychologist with SBUHB, said, "For practitioners and services, these findings are extremely useful. The study shows that a range of interventions can reliably improve well-being, which means we can tailor support according to the needs and preferences of different communities.
"Having evidence of this breadth and quality strengthens the foundation for developing accessible, flexible well-being programs across Swansea Bay and beyond."
More information: Lowri Wilkie et al, A systematic review and network meta-analysis of randomized controlled trials of well-being-focused interventions, Nature Human Behaviour (2026). DOI: 10.1038/s41562-025-02369-1
Provided by Swansea University
This story was originally published on Medical Xpress. 2026-01-15T18:33:47Z